A study demonstrated that Quantum Dots can cross the blood-brain-barrier to a small extend via the blood stream and end up into the brain tissue.

 

It is very challenging to deliver drugs to the brain because the blood brain barrier functions as a gatekeeper guarding the brain from exogenous substances.

In a recent study bioconjugated Quantum Dots were injected intraperitoneally (meaning into the body cavity) into mice and their distribution in the body was investigated [1]. Scientists found, that the Quantum Dots reached the blood circulation and mainly accumulated within the spleen, the liver and the kidney (correlating very well with other studies). However, a very small but still considerable amount ended up in the brain. Although most of the particles resided in blood vessels of the liver, the kidney and the brain, a few reached the brain tissue.

 

 

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